Objetivos: Determinar a prevalência e características sociodemográficas associadas ao uso de benzodiazepínicos entre idosos residentes. RESUMO. O objetivo deste estudo foi caracterizar o perfil farmacoepidemiológico de benzodiazepínicos (BZDs) em indivíduos assistidos em Unidades de. Abstract. The aim of this study was to compare benzodiazepine (bzd) prescriptions for adults and older adults regarding appropriate use indicator.
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Embora alivie o “nervoso”, o uso crônico de benzodiazepínicos tampona o sofrimento .. musicmarkup.info 4. Boltanski L. Benzodiazepine. Cite. Download. Share · Tweet · Email. PubChem CID: Structure: musicmarkup.info musicmarkup.info Avaliação do padrão de sono em insones usuários de benzodiazepínicos e análise da trazodona como medicação substitutiva Download full-text PDF.
About the authors Abstract The aim of this study was to compare benzodiazepine bzd prescriptions for adults and older adults regarding appropriate use indicator. Appropriate use indicators were used: appropriate drug, with adequate posology and period of use; as well as the use of a single bzd, as anxiolytic for less than 3 months in depression treatment with antidepressants, use for less than 2 months if associated to an antidepressant and no use of long-acting bzd in older adults. The minority of prescriptions had indication for the use of bzd Only 5. A minority of prescriptions for adults and older adults was appropriate. Benzodiazepine; Unified Health System; Drug prescription; Rational use of drugs Introduction Benzodiazepines constitute a group of psychotropic more commonly used in the clinical practice due to their four main actions: anxiolytic, hypnotic, anticonvulsive and muscle relaxant In: Silva P, organizador.
Discussion The present study verified a predominance of benzodiazepine prescription for the adults treated at the mental health clinic. The inappropriate use of these psychotropic was observed in adults as well as in older adults, and a minority of the prescriptions was rational and had the recommended period of time for the use of benzodiazepines The profile of the population studied was mainly women, married individuals, with a family history of mental disorders and using benzodiazepines, using other psychotropic and polypharmacy, and without the monitoring of a psychologist.
The prevalence of the use of psychotropic in women, benzodiazepine among them, was observed in several studies Cad Saude Publica ; 26 6 Rev Saude Publica ; 42 4 Antidepressants were the most prescribed psychotropic associated to benzodiazepine.
This trend was also observed by Souza et al. The association of benzodiazepines and antidepressants was referred to as the most common one in the beginning of the treatment of depression, due to the presence of symptoms such as anxiety and insomnia Rev Bras Psiquiatr ; 31 Supl. However, scientific evidence recommend the use of benzodiazepine as an adjuvant in treating depression only during the first four weeks of the treatment, its prolonged use is not recommended due to adverse effects Anxiety Disorders Drug Treatment Guidelines Anxiety disorders drug treatment guidelines.
Chronic diseases were more frequent in older adults, a fact that may be justified by physiological changes related to the aging process It was observed in adults a more frequent presence of four or more comorbidities, indicating a higher number of psychiatric diseases per individuals in this group.
Polypharmacy was frequent in adults and older adults, which corroborates with the results from the older adults studied by Noia et al. Clonazepam and diazepam were the most prescribed benzodiazepines in this study. This result differed from the ones found in the studies by Noia et al.
Vicente Sanchez et al. A minority of prescriptions had indication for benzodiazepine use in adults and older adults; bromazepam and clonazepam were the drugs more adequately prescribed for adults and, mainly clonazepam for older adults.
Estazolam, midazolam and nitrazepam were less prescribed and had no indication for use. This could be justified by the fact that estazolam and nitrazepam are indicated for insomnia treatment Greenwood Village: Thomson Micromedex; . This dug should be used with precaution in this age group due to the risk of ataxia and oversedation, and the recommendation for dose adjustment was observed in only this prescription. Woelfel et al. Use of potentially inappropriate medications in an ambulatory Medicare population.
Consult Pharm ; 26 12 Similarly to alprazolam, three lorazepam prescriptions for older adults were inappropriate due to the risk of potentiating sedation Miriam O. Bula de medicamento..
Midazolam is preferably used as anxiolytic and sedative preoperatively due to its fast absorption, rapid onset and short elimination half-life Therefore, its use is not recommended for clinical practices.
In the present study, only one prescription for this drug was found. It was observed that adults and older adults only used one benzodiazepine, which is adequate according to WHO recommendation Ginebra: OMS; It was also observed that the majority of the depressed individuals used benzodiazepine associated to antidepressant, which is correct according to Mantley et al.
However, the period of time using benzodiazepine for the treatment of depressive disorders up to two months when associated to antidepressants and anxiety for a time period no longer than three months According to the Brazilian Psychiatric Guideline Projeto diretrizes.
Beers criteria Benzodiazepine pharmacology and central nervous system — mediated effects. Nevertheless, they are still commonly used in this population which can be justified according to Paquin et al.
Risk versus risk: a review of benzodiazepine reduction in older adults. Expert Opin Drug Saf ; 13 7 A study conducted in Quebec evaluated, similarly to the present study, some adequacy criteria in the use of benzodiazepines in older adults.
Despertarse a menudo y tener dificultad para volver a dormirse. Sentirse irritables, ansiosas o deprimidas.
Tener olvidos frecuentes. Tener dificultad para concentrarse. El insomnio puede afectar su vida diaria.
Puede afectar su trabajo y las relaciones personales. Cambios en el horario de trabajo por ej.
Luego de que desaparecen estos desencadenantes, el insomnio puede continuar y ocasionar el trastorno de insomnio. Participants reported chronic consumption of the medication from six months to 40 years ; none of them used benzodiazepines at a dose higher than that recommended by the clinical and pharmacological guidelines, although they reported changing the type of benzodiazepine consumed. Because my husband fell ill, we went to a nearby city They had to prescribe me a sedative.
They took me to the doctor, and he prescribed Clonazepam.
It worked. There are days when we feel nervous for no reason. At other times, we keep thinking about being old, about our children scattered here and there They all seem happy.
There are days when not a single person comes around here to talk to me. I was so worried. Then he prescribed this medication. For old people, a sedative helps us bear the pain and the problems better Rio de Janeiro: Editora Fiocruz; ; p.
All ethnographic, interpretative, and statistical literature about nervous states is somehow related to the issue of labor and social reproduction. Historically, a division of roles and spaces has been recognized, in which men had duties performed in the public and external space, while women were predominantly destined to private and domestic spaces. Therefore, considering the interdependence between gender and social class, this scenario was profoundly modified when women began leaving the house to work.
Psic Teor Pesq. Rio de Janeiro: Editora Fiocruz; , p. He stopped drinking and I got better. I think these me dications are.. You get addicted to that medication. The blister pack there has about 10 pills left Rev Latino-Am Enfermagem.
It was horrible. Similar evidence of significant psychological dependency, concomitantly with the underestimation or denial of potential side effects of benzodiazepines, was detected among older North American adults, with a strong resistance to withdrawal of the medication.
Older primary care willingness to consider discontinuation of chronic benzodiazepines.
Gen Hosp Psychiatry. Any doctor can prescribe the medication benzodiazepine for us. A similar result was observed among Brazilian farm workers. She female employee of the service already knows.